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Casa Santo Stefano

Sicilian restaurant in a 1925 Ybor City macaroni factory, serving pasta, seafood, and wines imported from family businesses in Sicily.

About

Casa Santo Stefano occupies a former macaroni factory from 1925 in Ybor City, bringing Sicilian cooking and products directly to Tampa. The menu centers on maccheroni and other pasta, alongside steaks, seafood, and regional specialties like scacciata. The wine list holds hundreds of Sicilian selections. Hand-painted tiles and tabletops imported from a family workshop in Caltagirone, Sicily, cover the backsplashes and counters. The restaurant also imports cheese and extra-virgin olive oil from family businesses back home. Santo's Drinkeria offers Sicilian street food, desserts, and cocktails alongside the wine program. Curbside pickup, catering, and group reservations are available, with free parking across the street in the Columbia lot.